Bhat CS, et al. - Via the medical records of 46 children under the age of sixteen with a diagnosis of chronic non-bacterial osteitis (an autoinflammatory disorder that predominantly affects metaphyses of long bones) between 2005 and 2018, the researchers examined the response to pamidronate by conducting whole-body magnetic resonance imaging (WB-MRI) in a tertiary health center. All those who were administered pamidronate were recruited. Pre- and post-treatment WB-MRI was available for 40 subjects. Out of 150 cumulative lesions that were ascertained prior to the treatment, 45 were left post-treatment. With a complete resolution of all lesions, 17 subjects had a great response and 9 got worse during or after the treatment with pamidronate. About 82.3% of the lesions resolved fully with a great response in the vertebral disease. Hence, through this study that explained the experience with pamidronate in a tertiary health center using WB-MRI as a marker of disease activity, it was concluded that pamidronate was well endured in the cohort and treatment response was reasonably good.