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Efficacy of ginger (Zingiber officinale) in ameliorating chemotherapy-induced nausea and vomiting and chemotherapy-related outcomes: A systematic review update and meta-analysis

Journal of the Academy of Nutrition and Dietetics Sep 17, 2019

Crichton M, et al. - In adult cancer patients receiving chemotherapy, researchers investigated how the incidence, duration, and severity of chemotherapy-induced nausea and vomiting and outcomes associated with chemotherapy-induced nausea and vomiting (eg, quality of life and fatigue) can be influenced by ginger supplementation dose and duration vs placebo or standard antiemetic medication, via this systematic review with meta-analyses. They explored 5 electronic databases until April 2018 and identified 18 relevant articles. With supplementation ≤ 1 g/day for duration > 3 days, the chance of acute vomiting was attenuated by 60%, than control groups. In correlation with ginger supplementation of any dose for duration < 3 days, a decrease in the probability of fatigue by 80% was reported. Experts concluded that chemotherapy-induced vomiting, as well as fatigue, might be benefited from ginger supplementation. No link was found between ginger and chemotherapy-induced nausea and other chemotherapy-induced nausea and vomiting-related outcomes because of clinical heterogeneity.
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