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Efficacy of combined surgery and 125I seed brachytherapy for treatment of primary mucoepidermoid carcinoma of the parotid gland

Head & Neck May 30, 2019

Wu ZY, et al. - In this retrospective analysis, researchers determined the efficacy and safety of surgery in combination with postoperative 125I seed brachytherapy to treat the parotid gland's primary mucoepidermoid carcinoma (MEC). The study sample consisted of 108 patients with MEC treated with surgery plus postoperative 125I seed brachytherapy between 2004 and 2016. Data reported that the 5- and 10-year overall survival were 98.8% and 95.8%, respectively. Poor prognostic factors were age ≥ 60 years and T4 disease. There were minor toxicities associated with acute radiation. Overall, the authors concluded that surgery plus 125I seed brachytherapy seems to be an effective treatment for MEC parotid gland, capable with few complications of delivering satisfactory results.
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