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Efficacy of additional corticosteroid in a multimodal cocktail for postoperative analgesia following total knee arthroplasty: A meta-analysis of randomized controlled trials

Pain Practice Jan 04, 2019

Chai X, et al. - Researchers performed this meta-analysis of randomized controlled trials (RCTs) to assess the efficacy of an additional, local injection of corticosteroid in terms of pain relief and knee function recovery after total knee arthroplasty (TKA). For data extraction and meta-analysis, they identified 9 RCTs involving 727 knees as eligible. Outcomes revealed achievement of improved postoperative pain, enhanced knee functional recovery, and shortened hospital stays following TKA on adding additional corticosteroid to a multimodal cocktail. However, local injection of corticosteroids seemed to have no effect on reducing nausea and vomiting.
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