In Seo S, et al. - A 2-L-2-L polyethylene glycol-based solution with ascorbic acid (PEG/Asc) was compared with sodium picosulfate/magnesium citrate (SP/MC) using a split method in bowel cleansing efficacy, tolerability, and safety, and the factors influencing inadequate bowel preparation were determined. No notable variation was found in overall bowel cleansing efficacy between PEG/Asc and SP/MC. SP/MC demonstrated better tolerability and a safety profile compared to PEG/Asc. Later colonoscopic starting time with the split method was an independent factor for inadequate bowel preparation.