Shah S, et al. - An investigation was pursued with regard to the efficacy and safety of a botanical-based Rosa E pigmentation serum in healthy fair skin female volunteers with wrinkles, skin tone, and pigmentation. This serum was discovered to be safe and effective in substantially reducing the skin pigments, improving the skin tone, and antiwrinkle properties instrumentally, clinically, and via self-evaluation by volunteers. The longer the Rosa E was used, the better were the results seen in these evaluations.