Misumida N, et al. - Considering that there is an increased risk for subsequent ischemic events in patients who undergo percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS), researchers analyzed randomized controlled trials that compared short-term (≤ 6 months) to long-term (≥ 12 months) dual antiplatelet therapy (DAPT) following PCI for ACS to assess if short-term DAPT is inferior to standard or long-term DAPT in this patient population. Overall, they included a total of 10 randomized controlled trials, with 12,696 patients. Clopidogrel and second-generation drug-eluting stents were used in most of the studies. According to findings, no increased risk of myocardial infarction or stent thrombosis was observed in relation to short-term DAPT (< 6 months) vs long-term DAPT after PCI for ACS.