Efficacy and safety of DFN-15, an oral liquid formulation of celecoxib, in adults with migraine: A multicenter, randomized, placebo-controlled, double-blind, crossover study
Neuropsychiatric Disease and Treatment Nov 15, 2017
Munjal S, et al. - The efficacy and safety of DFN-15 (an oral liquid formulation of celecoxib) in adults with migraine were investigated. Furthermore, the researchers evaluated variability in patient-identified most bothersome symptom (MBS) across 3 migraine attacks. For the 2-hour pain-free endpoint, both doses of DFN-15 outperformed placebo, but the differences were not statistically significant due to a carryover effect with placebo. DFN-15 120 mg was being further developed for the management of acute migraine as the response to both doses was similar.
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