Adam I, et al. - Researchers performed a systematic review and meta-analysis to obtain an overall stronger evidence of the outcomes of artemisinin-based combination therapy (ACT) in the treatment of uncomplicated falciparum malaria from the existing literature in Sudan. This review suggested an overall high malaria treatment success (98%). Compared to artesunate + sulfadoxine–pyrimethamine, artemether + lumefantrine regimen showed higher efficacy. Overall the regimens were associated with non-serious low rates of adverse drug reactions.