Gracies JM, et al. - Authors aspired to illustrate single abobotulinumtoxinA injection efficacy in lower limb vs placebo for adults with chronic hemiparesis. Additionally, they gauged the long-term safety and efficacy of repeated injections. The administration of single abobotulinumtoxinA (Dysport Ipsen) reduced muscle tone in the case of chronic hemiparesis. Repeated administration over a year appeared to be well-tolerated and resulted in improved walking speed and the tendency of achieving community ambulation.