Cheon HI, Kim JH, Kim BJ, et al. - Researchers conducted this multicenter, randomized, evaluator/subject‐blind, active‐controlled, split‐face study to compare the effectiveness and safety between DIVAVIVA medium, a novel biphasic hyaluronic acid filler incorporating lidocaine, and Restylane Perlane Lidocaine for moderate to severe nasolabial folds. Data reported that the mean change of WSRS at week 24 was −0.61 ± 0.54 in DIVAVIVA medium group and −0.59 ± 0.49 in Restylane Perlane Lidocaine group. For the correction of moderate to severe nasolabial folds, DIVAVIVA medium has comparable efficacy and safety to Restylane Perlane Lidocaine.