Berlot G, et al. - Researchers sought to study adult patients with septic shock in intensive care unit (ICU) treated with ivIgGAM from august 1999 to december 2016 to assess the impacts of the timing of administration of IgM- and IgA-enriched intravenous polyclonal immunoglobulins on the outcome of these patients. They used parametric and nonparametric tests and logistic regression for statistic analysis. Findings suggested an association of earlier administration of ivIgGAM with decreased risk of in-ICU mortality both in patients with septic shock caused by any pathogens and in patients with MDR-related septic shock.