Shirozu K, et al. - In this study including patients undergoing living-donor kidney transplantation (LDKT), researchers determined the impacts of preoperative plasma exchange therapy (PEX) on blood coagulation parameters and blood loss during the perioperative period using rotational thromboelastometry (ROTEM). They compared ROTEM parameters, standard laboratory test parameters, bleeding volume, and transfusion volume between PEX (ABO incompatible with PEX) and non-PEX group (ABO compatible without PEX). They noted decreased platelet contribution to clot strength, as measured by ROTEM, related to increased blood loss in the PEX group during surgery and the intensive care unit stay.