Kang Z, et al. - Experts conducted a meta-analysis to examine the impacts of tight glycemic control (TGC) on surgical mortality and morbidity via a search of PubMed, EMBASE, and CENTRAL from January 1, 1946, to February 28, 2018. In the final analysis, 26 trials including a total of 9315 subjects were involved. They discovered that perioperative TGC (the upper level of glucose goal ≤ 150 mg/dL) was related to the significant reduction of short-term mortality, cardic surgery mortality, non-diabetic patients mortality and some postoperative complications compared to liberal control. Findings suggested an association of TGC with decreased risks for acute kidney injury, sepsis, surgical site infection, atrial fibrillation, and increased risks of hypoglycemia and severe hypoglycemia. Results of this study suggested that perioperative TGC will benefits patients when it is done carefully regardless of increased risks of hypoglycemic events.