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Effects of isavuconazole on the plasma concentrations of tacrolimus among solid-organ transplant patients

Antimicrobial Agents and Chemotherapy Sep 09, 2017

Rivosecchi RM, et al. - In this work, researchers sought for interaction between isavuconazole and tacrolimus among 55 organ transplant recipients. Findings revealed significant interpatient variability in the magnitude of the drug interaction. They recommended not adjusting tacrolimus doses uniformly but, rather, be guided by therapeutic drug monitoring.
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