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Effects of iron deficiency anemia on peripapillary and macular vessel density determined using optical coherence tomography angiography on children

Graefe's Archive for Clinical and Experimental Ophthalmology Mar 09, 2020

Korkmaz MF, et al. - In this investigation involving 32 patients with iron deficiency anemia (IDA) [study group, mean age was 12.22 ± 4.48 years (ranged 5–18 years)] and 30 healthy children [control group, mean age was 12.37 ± 3.76 years (ranged 6–18 years)], researchers assessed retinal vascular parameters by optical coherence tomography angiography (OCT-A) in IDA. There was a negative correlation between serum iron, TIBC, and capillary plexus density. There was a positive correlation between MCV and ferritin values and capillary plexus density. The capillary plexus density was significantly lower for IDA. In young IDA patients, retinal microvascular changes were detected before significant ocular anomalies, particularly ischemic changes, developed.
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