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Effects of hypoglycaemia on working memory and regional cerebral blood flow in type 1 diabetes: A randomised, crossover trial

Diabetologia - Clinical and Experimental Diabetes and Metabolism Feb 12, 2018

Gejl M, et al. - Experts aspired to compare cognitive functioning and associated brain activation patterns during hypoglycaemia (plasma glucose [PG] just below 3.1 mmol/l) and euglycaemia in individuals with type 1 diabetes mellitus. Working memory performance was impaired during hypoglycaemia (mean PG 2.9 mmol/l). An association was found between altered performance and significantly increased blood flow in the striatum, a part of the basal ganglia implicated in regulating motor functions, memory, language, and emotion.
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