Hakimi CS, et al. - Due to the clinical use of fibrinogen and platelet concentrate transfusion to improve haemostasis and reduce bleeding, researchers have analyzed their functional effects on coagulation and platelet function in 42 patients with ongoing bleeding after cardiac surgery. The results obtained from the observational study indicate that fibrinogen infusion increased the fibrinogen concentration and clot stability but did not affect the platelet aggregation. It was noted that platelet transfusion improved arachidonic acid- and TRAP-induced platelet aggregation and increased platelet count but did not significantly affect coagulation. The findings show improved coagulation and platelet function after fibrinogen and platelet transfusion in patients who have been bleeding after the cardiac operation.