Zhu Y, Gou H, Ma L, et al. - Researchers undertook a prospective hospital-based cohort study to assess if epilepsy (PSE) occurrence after stroke can be better prevented by a double-dose statin treatment. Of 1,152 selected patients with newly diagnosed ischemic stroke who were hospitalized between March to August 2017, 1,033 were followed-up. Two groups of patients were defined: (1) standard-dose (20 mg atorvastatin or 10 mg rosuvastatin,daily oral; 788 patients); and (2) double-dose (40 mg atorvastatin or 20 mg rosuvastatin, daily oral; 245 patients). A significantly lower incidence of PSE was observed in the double-dose group vs the standard-dose group. A reduction in PSE incidence was brought about by increasing the dose of statin treatment during the acute phase of ischemic stroke.