Ulusoy H, Kangalgil M, Küçük AO, et al. - Researchers conducted this prospective, single-center, observational cohort study to examine the impacts of different lipid emulsions on changes in concentrations of adipokine and cytokine and their association with mortality in patients. Patients were estimated to require more than ten days of parenteral nutrition and they were treated with soybean oil-based or olive oil-based parenteral lipid emulsions. Over a 25-month period, 145 patients were evaluated for eligibility, and 40 patients were analyzed as a result. An association was found between survival and percentage changes in adiponectin, resistin, and visfatin concentrations. Medical nutritional therapy affects adipokine and cytokine responses during the sepsis process, and adipokines may serve as functional prognostic biomarkers in critically ill patients with sepsis.