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Effects of dexmedetomidine on intraoperative hemodynamics, recovery profile and postoperative pain in patients undergoing laparoscopic cholecystectomy: A randomized controlled trial

BMC Anesthesiology Mar 07, 2021

Ye Q, Wang F, Xu H, et al. - Researchers aimed at determining the optimal dose of dexmedetomidine for patients undergoing laparoscopic cholecystectomy that may aid in maintaining hemodynamic stability, preventing cough and minimizing postoperative pain. They randomly divided 120 patients into D1, D2, D3 and NS groups, to administer dexmedetomidine 0.4, 0.6, 0.8μg/kg and normal saline, respectively. Based on outcomes, they suggest that in patients undergoing laparoscopic cholecystectomy, intravenous infusion of 0.6μg/kg dexmedetomidine prior to induction can aid in maintaining hemodynamic stability, decreasing cough during emergence, and relieving postoperative pain.

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