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Effects of depth of neuromuscular block on surgical conditions during laparoscopic colorectal surgery: A randomised controlled trial

Anaesthesia May 13, 2018

Koo BW, et al. - Researchers determined the impacts of deep neuromuscular block on surgical conditions during laparoscopic colorectal surgery. The number of abrupt increases in intra-abdominal pressure intra-operatively as well as intra-operative restoration of spontaneous breathing, number of surgical requests for additional neuromuscular blockade, surgical rating of operating conditions and patient satisfaction were assessed for cases randomly allocated to either moderate (train-of-four count 1–2 maintained and antagonised with neostigmine) or deep (post-tetanic count 1–2 maintained and reversed with sugammadex) levels of neuromuscular blockade. In patients undergoing elective laparoscopic colorectal surgery, better surgical conditions were seen with deep neuromuscular blockade vs moderate neuromuscular blockade, as measured by a reduction in the incidence of intra-abdominal pressure alarms.
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