• Profile
Close

Effects of cancer stage and grade on fertility preservation outcome and ovarian stimulation response

Human Reproduction Mar 06, 2019

Volodarsky-Perel A, et al. - Researchers performed this retrospective cohort study to examine how the stage and grade of malignancy influence the fertility preservation outcome in females. Data of all fertility preservation treatment cycles among women with cancer at the reproductive unit of the McGill University Health Centre in the period from 2008 to 2017 were evaluated. They analyzed a total of 147 patients in the final analysis. A higher dose of gonadotropin was required for women with high-stage cancer (n = 64) required that those with low-stage cancer (n = 83). The two groups were similar regarding the number of retrieved mature oocytes (9 (7–13) vs 8 (5–12)) and vitrified oocytes (10 (7–15) vs 10 (7–13)). However, the low-stage group displayed higher fertilization rate (82.7% vs 71.5%) and the number of vitrified embryos (6.2 ± 3.2 vs 4.3 ± 2.1) in cycles where fertilization of all retrieved oocytes was performed. The multivariate logistical analysis suggested a significant association between low-grade cancer and retrieval of over 10 mature oocytes.
Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay