Schiavon CA, et al. - In this randomized trial, researchers investigated how 24-hour blood pressure (BP) profile, BP variability, and resistant hypertension prevalence are influenced by bariatric surgery performed on obese patients with grade 1 and 2 using at ≥ 2 antihypertensive drugs at maximal doses or > 2 at moderate doses. For 12 months, either Roux-en-Y Gastric Bypass (RYGB) combined with medical therapy or medical therapy alone were used to treat patients. The study sample consisted of 100 patients (76% female; body mass index: 36.9±2.7 kg/m²). According to the findings, a markedly attenuated use of antihypertensive medications was noted among those who received RYGB. In addition, RYGB promoted similar 24-hour BP profile and nondipping status. Improvement in BP variability was evident as a result of bariatric surgery, which could also possibly attenuate the burden of resistant hypertension related to obesity.