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Effects of anesthetics on postoperative 3‐month neuroendocrine function after endoscopic transsphenoidal non‐functional pituitary adenoma surgery

Acta Anaesthesiologica Scandinavica Jun 04, 2020

Oh H, Yhim HB, Yoon HK, et al. - Researchers examined the 3‐month postoperative neuroendocrine functional outcomes in patients undergoing endoscopic transsphenoidal surgery (ETS), under sevoflurane vs propofol anesthesia, for removal of non‐functional pituitary adenomas (NFPAs). They identified 356 patients who underwent ETS for removal of NFPAs under sevoflurane‐remifentanil anesthesia (sevoflurane group, = 103) or propofol‐remifentanil anesthesia (propofol group, = 253); of these, they selected 92 patients in each group for assessment of the 3‐month postoperative neuroendocrine functional outcomes. Outcomes revealed similar effects of both sevoflurane‐remifentanil and propofol‐remifentanil anesthetic techniques on postoperative 3‐month neuroendocrine functional outcomes, indicating that propofol and sevoflurane can be freely employed in such cases in terms of postoperative intermediate‐term neuroendocrine functional outcome.

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