Goss AM, Dowla S, Pendergrass M, et al. - Using a family-based intervention with a 2-week feeding phase and 6-week free-living phase, researchers contrasted the effects of an individualized weight-maintaining CHO-restricted diet (CRD) vs a standard, fat-restricted diet (FRD) in children and adolescents with NAFLD on reduction in hepatic lipid content and insulin resistance. Thirty-two children/adolescents, aged 9 to 17, with obesity and NAFLD were randomized to a CRD or FRD for 8 weeks. The authors discovered significantly greater decreases in insulin resistance, abdominal fat mass, and body fat mass in response to the CRD vs FRD. Such results indicate that consumption of a moderately CHO-restricted diet in adolescents with NAFLD may result in decreased hepatic lipid as well as improvements in body composition and insulin resistance, even in the absence of deliberate caloric restriction.