Pullan RL, et al. - Researchers conducted this cluster-randomized controlled trial to evaluate the impacts of alternative mass treatment approaches on community soil-transmitted helminth infection. For this investigation, 120 community units serving 150,000 households in Kenya were randomized (1:1:1) to receive albendazole through yearly school-based treatment targeted at 2-14-year-olds or yearly or twice-yearly community-wide treatment targeted at all ages. In reducing the prevalence and intensity of hookworms, the authors concluded that community-wide treatment had greater efficacy vs school-based treatment (with little added benefit from treatment every 6 months) and showed equitable coverage and effects. No albendazole-related adverse events were reported.