Pullan RL, et al. - School-based deworming programs may lower morbidity related to soil-transmitted helminths in children but may have no impact on transmission in the wider community, so researchers investigated how different large-scale treatment tactics influence community soil-transmitted helminth infection. They randomly assigned (1:1:1) 120 community units (clusters) serving 150,000 households in Kenya in this cluster-randomized controlled trial to receive albendazole through annual school-based treatment targeting of 2–14-year old children or annual or biannual community-wide treatment targeting all ages. Study outcomes suggest a higher efficacy of community-wide treatment in lowering hookworm prevalence and intensity vs school-based treatment. Treating every 6 months seems to have a little additional benefit.