Shakya P, et al. - This paper encompassed an assessment of the effectiveness of non-steroidal anti-inflammatory drugs (NSAIDs), a PGE2 synthesis blocker with the goal of reducing the symptoms among primary hypertrophic osteoarthropathy (PHO) patients. The conclusion drawn was that NSAIDs were effective in improving arthralgia or arthritis symptoms in maximum PHO patients. Hence, the use of NSAIDs was recommended in the case of PHO patients for treating arthralgia or arthritis.