Sens F, et al. - This study assessed renal recovery and survival in dialysis-dependent acute cast nephropathy patients treated with chemotherapy plus intensive hemodialysis (IHD) with an adsorbent polymethylmethacrylate membrane (IHD-PMMA). High rates of renal recovery and survival were obtained in association with early free light chains (FLC) removal by IHD-PMMA combined with chemotherapy in patients with dialysis-dependent myeloma cast nephropathy.