Zomer E, et al. - This paper resolved to disclose the cost-effectiveness of two bespoke severe mental illness (SMI)-specific risk algorithms compared with standard risk algorithms, for primary cardiovascular disease (CVD) prevention in those with SMI. The findings displayed that the general population lipid and SMI-specific body mass index (BMI) algorithms performed equally well. As a result of the ease and acceptability of use of SMI-specific BMI algorithm (blood tests not required), it was presented as an attractive algorithm to implement in clinical settings.