Buck ES, et al. - This study was attempted to examine the available data related to the prevention of recurrent urinary tract infection (rUTI) in postmenopausal women with vaginal estrogen preparations and provide the urologic community with the confidence to distinguish and treat the genitourinary syndrome of menopause (GSM). Researchers carried out to search MEDLINE and the Cochrane Central Register of Controlled Trials databases to distinguish studies utilizing vaginal estrogen in the treatment of urological conditions related to rUTI and GSM. The finding revealed the effectiveness of local estrogen preparations for the treatment of rUTIs. In this high yield review, a framework was provided for evaluating GSM, prescribing recommendations for local vaginal hormone preparations, and a summary of the substantial data supporting the new 2019 American Urological Association/Canadian Urological Association/Society of Urodynamics, The evidence suggested that for rUTI, the female Pelvic Medicine and Urogenital Reconstruction Guidance for local vaginal estrogen use.