Effect of vasoactive therapy used for brain-dead donors on graft survival after kidney transplantation
Transplantation Proceedings May 10, 2018
Birtan D, et al. - Given the paramount significance of hemodynamic optimization during donor care, researchers investigated the effects of vasoactive drugs used in the cadaveric donor care on post-transplant renal graft functions. Results of the Pearson correlation analysis test showed noradrenaline use to be related to a decrease in graft loss and graft rejection. Noradrenaline but not dopamine used in cadaveric donor care reduced the graft rejection rate and graft loss, presumably by improving hemodynamic stability and organ perfusion, however, no particular reason was identified.
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