Vianzon V, et al. – Experts used a human bronchial epithelial cell culture model (16HBE14o–) to assess the mechanism by which vaccine–induced human IgG antibodies affect colonization by serogroup B (MenB) or C (MenC) strains. New insights into the mechanism by which high avidity anticapsular antibodies elicited by polysaccharide–conjugate vaccines affect meningococcal colonization, were given by this study. Results suggested that any effect on colonization by IgG elicited by outer membrane vesicle (OMV)– or Factor H binding protein (FHbp)–based vaccines seemed to involve a different mechanism.