Koyama T, Ozaki E, Kuriyama N, et al. - Utilizing data from the J‐MICC (Japan Multi‐Institutional Collaborative Cohort) Study, researchers intended to determine if there is an association between sedentary time and mortality with regard to leisure‐time physical activity with or without cardiometabolic diseases like hypertension, dyslipidemia, and diabetes mellitus. The sample consisted of 64,456 participants (29,022 men, 35,434 women). During the 7.7 years of follow-up, 2,257 candidates died. Data reported that the corresponding hazard ratios for each 2‐hour increment in sedentary time among participants with all factors, no factors, hypertension, dyslipidemia, and diabetes mellitus were 1.153, 1.125, 1.202, 1.176, and 1.272, respectively. In a large Japanese population, the link between sedentary time and increased mortality is stronger among patients with hypertension, dyslipidemia, and diabetes mellitus, regardless of leisure-time physical activity.