Weiner M, Goh SM, Mohammad AJ, et al. - Given that age is a risk factor for organ damage, adverse events, and mortality in microscopic polyangiitis (MPA) and granulomatosis with polyangiitis (GPA), researchers intended to determine if there is an association between treatment and damage, hospitalizations, and causes of death in elderly patients. Consecutive individuals from Sweden, the United Kingdom, and the Czech Republic diagnosed between 1997 and 2013 were involved. Treatment with cyclophosphamide (CYC), rituximab (RTX), and corticosteroids the first 3 months has been recorded. Treatment data for 167 of 202 patients had been available. According to findings, immunosuppressive treatment with CYC or RTX in elderly patients with MPA and GPA was correlated with development of less permanent organ damage and was not related to hospitalization. During the first 3 months, higher doses of corticosteroids, however, was linked to treatment-related damage and fatal infections.