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Effect of topical hypotensive medications for preventing intraocular pressure increase after cataract surgery in eyes with glaucoma

American Journal of Ophthalmology Mar 26, 2019

Hayashi K, et al. - In this randomized clinical study, 165 eyes of 165 cases were examined to assess consequences of a topical intraocular pressure (IOP)-lowering medication to prevent an IOP increase after cataract surgery in eyes with glaucoma. They observed no variation in mean IOP at 1 h preoperatively and at the end of surgery. But, an increase in mean IOP significantly between 4 and 8 h postoperatively, and then a decrease at 24 h postoperatively were also noted. Significantly lower mean IOP in the brinzolamide group was recorded as compared to in the travoprost or timolol group at 4, 6, and 8 h postoperatively. But, it did not deviate significantly among people at 2 and 24 h postoperatively. A significantly lower incidence of an IOP spike was reported in the brinzolamide group than in the travoprost and timolol groups.
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