Griesinger G, Blockeel C, Pierzynski P, et al. - Researchers aimed at ascertaining the effect of a single oral dose of nolasiban 900 mg administered 4 h before embryo transfer (ET) on pregnancy rates in women undergoing IVF via analyzing three randomized, double-blind, placebo-controlled trials, which randomized 1,836 individuals. Patients undergoing ET following IVF/ICSI in 60 fertility centers in 11 European countries were randomized to receive a single oral dose of nolasiban 900 mg (n = 846) or placebo (n = 864). A single oral dose of nolasiban 900 mg was identified to be linked with an elevated ongoing pregnancy rate of an absolute 5% (relative 15%) in this individual patient data (IPD) meta-analysis of three clinical trials.