Yu JJ, et al. - Experts studied the effect of liver resection on perioperative circulating tumor cells (CTCs) and found that the prognostic significance of the surgery caused changes in CTC counts in patients with hepatocellular carcinoma (HCC). For this investigation, 139 patients with HCC were consecutively recruited. Findings suggested an association of surgical liver resection with an increase in CTC counts. In patients with HCC, increased postoperative CTC numbers were correlated with a worse prognosis.