Yang D, et al. – This multicenter study aimed to examine the effects of different diameters of Solitaire retrievers on outcomes. Based on the size of Solitaire retrievers, there was no evidence of a differential effect of intra–arterial therapy. Favorable reperfusion was correlated with the deployment of a small stent in patients with atherosclerotic disease.

• The clinicians enrolled 628 patients from the Endovascular Treatment for Acute Anterior Circulation Ischemic Stroke Registry.
• Out of them, 256 were treated with the Solitaire 4-mm device and 372, with the 6-mm device.
• Using propensity score analysis, they matched patients treated with the 2 stent sizes.
• The successful outcome was reperfusion as measured by the modified Thrombolysis in Cerebral Infarction score immediately postprocedure and the dichotomized modified Rankin Scale score at 90 days.
• They also recorded symptomatic intracerebral hemorrhage and in-hospital mortality.

• Group outcomes did not differ after propensity score analysis.
• Moreover, in patients with atherosclerosis-related occlusion, the clinicians observed a higher reperfusion rate (P = .021) in the Solitaire 4 group, as well as a shorter time interval (P = .002) and fewer passes (P = .025).
• The small stent (OR, 3.217; 95% CI, 1.129–9.162; P = .029) and the propensity score acting as a covariate (OR, 52.84; 95% CI, 3.468–805.018; P = .004) were the independent predictors of successful reperfusion in patients with atherosclerotic disease on logistic analysis.