Effect of prior glaucoma surgery on intraocular pressure immediately after anti-vascular endothelial growth factor injection
Graefe's Archive for Clinical and Experimental Ophthalmology Nov 08, 2019
Lam J, Luttrell I, Ding L, et al. - In this single institution, experimental investigation, researchers characterized how the intraocular pressure (IOP) rise shortly after intravitreal anti-VEGF injections can be influenced by prior incisional glaucoma surgery. This analysis was performed on 10 eyes with a history of glaucoma surgery and 29 control eyes receiving anti-VEGF injections. In both surgical and control eyes, proliferative diabetic retinopathy was identified as the most frequent indication for intravitreal anti-VEGF injection. A significantly lower post-injection IOP rise and a faster recovery to within 10 mmHg of their pre-injection IOP was observed in eyes with prior incisional glaucoma surgery. For cases with a requirement of attenuation of post-injection IOP rise and with failed other less invasive measures, consideration may be given to incisional glaucoma surgery.
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