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Effect of preoperative tricuspid and/or mitral regurgitation on development of late right-sided heart failure after insertion of the HeartWare left ventricular assist device

The American Journal of Cardiology Nov 04, 2019

Gonzalez-Fernandez O, Bouzas Cruz N, Ferrera C, et al. - In this retrospective analysis, researchers determined the factors that could predict the development of late right-sided heart failure (RHF) in left ventricular assist device patients. From a single-centre, all adult patients who had HeartWare-VAD implantation as a bridge to transplantation were selected. The development of late RHF was reported in 16 (10.3%) patients from 156 implantations. Median time to late RHF onset was identified to be 182.5 (IQR 105-618) days. Older age at surgery was reported for patients developing late RHF. Patients presenting with late RHF exhibited a significantly higher rate of moderate or severe tricuspid regurgitation prior to implantation. The predictors of the occurrence of late RHF, which were identified in this study, were preoperative significant tricuspid regurgitation and mitral regurgitation following implantation.
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