Effect of pregnancy in arrhythmogenic right ventricular cardiomyopathy
The American Journal of Cardiology Dec 04, 2019
Wu L, Liang E, Fan S, et al. - By performing this study on retrospectively enrolled 157 women with arrhythmogenic right ventricular cardiomyopathy (ARVC), researchers inquired about the influence of pregnancy in these women. They studied data regarding pregnancy and cardiac outcomes. In 120 patients, 224 pregnancies were reported, including 30 (13.4%) spontaneous and 2 (0.9%) medical abortions. Documented cardiac adverse events were 12 in total, including 3 (2.5%) cases with new onset frequent premature ventricular contractions (PVC), previous PVC numbers rose more than 100% in 5 (4.2%), syncope was reported in 2 (1.7%), sustained ventricular tachycardia and heart failure needed hospitalization each in one patient (0.8%). Lower left ventricular ejection fraction (LVEF) was exhibited by women with cardiac events. A raised risk of all-cause mortality was observed in relation to earlier symptom onset age and reduced LVEF. Survival was not negatively affected by pregnancy. Overall, pregnancy appeared to be acceptable in ARVC, and increased risk of pregnancy as well as poorer long-term survival was reported in relation to the presence of decreased LVEF.
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