Oh TK, et al. - In this retrospective cohort study involving 24,929 patients admitted to a single tertiary academic hospital intensive care unit (ICU), researchers investigated the association between preadmission glucocorticoid (GC) therapy and 30-day mortality following admission to an ICU. Further, they determined the influence of daily GC dosage and type on this association. The patients regularly undergoing oral GC therapy were classified as preadmission GC users, and those with no history of GC use were classified as non-GC users. In all, 816 (3.3%) patients were preadmission GC users. Observations revealed increased 30-day mortality after ICU admission in association with preadmission GC use vs non-GC use. Higher prevalence of this association was noted among preadmission GC users with diabetes mellitus and among preadmission GC users who took > 5 mg/day of prednisolone and methylprednisolone.