Effect of pitavastatin and atorvastatin on regression of atherosclerosis assessed using intravascular ultrasound: A meta-analysis
Coronary Artery Disease Aug 10, 2018
Liu H, et al. - Researchers performed a meta-analysis of randomized-controlled trials to assess pitavastatin and atorvastatin with respect to the efficacy and safety. They searched PubMed, CENTRAL, Web of Knowledge, and ClinicalTrials.gov website and identified 11 trials with a total of 1,733 participants. They included studies that directly compared pitavastatin with atorvastatin and reported the outcome of low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), glycated hemoglobin, and intravascular ultrasound evaluation. Based on the findings, pitavastatin vs atorvastatin seemed to be less effective in attenuating LDL-C and elevating HDL-C level, however, they were not significantly different in inducing changes in glycated hemoglobin and intravascular ultrasound evaluation.
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