Singh AM, Kirsch JM, Patel MS, et al. - A prospective randomized study was designed to evaluate the impact of perioperative acetaminophen on pain management in patients undergoing rotator cuff repair. Researchers prospectively randomized a total of 57 individuals (mean age, 57.8 ± 9.55 years) who had undergone primary arthroscopic rotator cuff repair to one of three treatment groups. The results of this study exhibited that the perioperative acetaminophen represents an important component of multimodal analgesia in appropriately selected individuals undergoing shoulder surgery. This research illustrated a significant decrease in opioid consumption and resulted in improved overall pain control following primary arthroscopic rotator cuff repair.