Sugiura R, et al. - In this investigation, researchers determined the impact of pancreatic mass size on the diagnostic yield of endoscopic ultrasonography-guided fine-needle aspiration (EUS-FNA). Between May 2008 and December 2016, they searched the database at Hokkaido University Hospital and identified solid pancreatic lesions examined by EUS-FNA. Based on mass sizes, all lesions were stratified into five groups: groups A (< 10 mm), B (10–20 mm), C (20–30 mm), D (30–40 mm), and E (≥ 40 mm). A total of 788 solid pancreatic lesions were analyzed among 761 patients. The adverse event rates between the five groups were not significantly different. It was noted that the sensitivities and diagnostic accuracies of EUS-FNA for solid pancreatic lesions were higher for lesions ≥ 10 mm in size. Multivariate analysis demonstrated that pancreatic mass size was related to diagnostic accuracy.