Oldenburg CE, Pinsky BA, Brogdon J, et al. - Treatment with a single dose of oral azithromycin vs placebo among outpatients with SARS-CoV-2 infection did not correlate with a greater likelihood of being free of symptoms at day 14.

• Randomized clinical trial of azithromycin vs matching placebo included 263 participants with SARS-CoV-2 infection.

• Treatment with a single oral dose of azithromycin, 1.2 g, was linked with self-reported absence of COVID-19 symptoms at day 14 in 50% vs 50% in those receiving placebo; the results were not statistically significant.