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Effect of multimodal prehabilitation vs postoperative rehabilitation on 30-day postoperative complications for frail patients undergoing resection of colorectal cancer: A randomized clinical trial

JAMA Surgery Jan 27, 2020

Carli F, Bousquet-Dion G, Awasthi R, et al. - Researchers here investigated the extent to which a prehabilitation program influence 30-day postoperative complications in frail patients scheduled for colorectal cancer resection. They conducted a randomized clinical trial recruiting 110 frail patients undergoing colorectal surgery (87 [79.1%] minimally invasive) within an enhanced recovery pathway. Either before (Prehab group) or after (Rehab group) surgery, they implemented a multimodal program including exercise, nutritional, and psychological interventions. Outcomes revealed no effect of prehabilitation vs postoperative rehabilitation on postoperative complications (measured using the Comprehensive Complication Index). Further, the groups were similar concerning other postoperative outcomes.
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