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Effect of moderate and severe persistent hyperglycemia on outcomes in patients with intracerebral hemorrhage

Stroke Dec 03, 2021

Qureshi AI, Huang W, Lobanova I, et al. - In nondiabetic patients with intracerebral hemorrhage, an elevated risk of death or disability is conferred by persistent hyperglycemia (either moderate or severe).

  • This study included 1,000 patients with intracerebral hemorrhage enrolled within 4.5 hours of symptom onset.

  • Multivariate analysis showed higher 90-day death or disability in relation to both moderate (odds ratio, 1.8) and severe (odds ratio, 1.8) hyperglycemia, post-adjustments.

  • In cases without preexisting diabetes, an association of both moderate (odds ratio, 1.8) and severe (odds ratio, 2.0) hyperglycemia with 90-day death or disability was observed post-adjusting for potential confounders.

  • In patients with preexisting diabetes, there was no relation of moderate and severe hyperglycemia with 90-day death or disability.

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